oa SA Pharmaceutical Journal - Long-term antihistamine therapy revisited : review
|Article Title||Long-term antihistamine therapy revisited : review|
|© Publisher:||Medpharm Publications|
|Journal||SA Pharmaceutical Journal|
|Affiliations||1 Sefako Makgatho Health Sciences University and 2 Sefako Makgatho Health Sciences University|
|Publication Date||Jan 2015|
|Pages||12 - 16|
|Keyword(s)||Allergic rhinitis, Anti-inflammatory effects of antihistamines, Chronic urticaria, Insomnia and Long-term treatment antihistamines|
Allergic diseases are increasing all over the world, now affecting up to 40% of the population. The most frequently occurring allergic conditions include allergic rhinitis (hay fever), chronic sinusitis, atopic dermatitis, and chronic urticaria. The literature suggests that second-generation histamine 1 (H1) antihistamines are the preferred first-line therapy for most chronic allergic conditions, including allergic rhinitis and chronic urticaria. Patients taking these antihistamines report little to no adverse effects with long-term continuous treatment. Second-generation H1-antihistamines have been shown to exert an anti-inflammatory effect, and continuous administration may improve their efficacy.
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