Wound Healing Southern Africa - Volume 5, Issue 1, 2012
Volume 5, Issue 1, 2012
Author Alan WidgerowSource: Wound Healing Southern Africa 5 (2012)More Less
We have an ongoing struggle that tends to be unique to South Africa. Most likely, it reflects the constant quest of medical insurers to try and limit coverage of their plans to hospital-related events primarily, and to preventive medicine outside of these hospital events. While this is understandable from a cost-containment perspective, and while we all recognise that there is a limited pool of funds available for a massive volume of patients, wound care has fallen casualty to this philosophy for many years.
Author D. ChrysostomouSource: Wound Healing Southern Africa 5, pp 6 –10 (2012)More Less
The violin spider (Loxosceles parrami) is frequently encountered in Gauteng. The number of patients with spider bites increases in summer. Early treatment with a nanocrystalline silver dressing seems to alleviate symptoms, and lead to faster healing. Literature research has shown that spider bite wounds pose a challenge to practitioners, owing to difficulty of diagnosis and identification of the species. Nanocrystalline silver is known for its anti-inflammatory and antibacterial properties. In 11 cases of suspected spider bites, Acticoat was applied to the affected area. In each instance, clinical history, examination and digital photography were recorded. No positive identification of the spider was made in any of the cases. The evolution of eight lesions was favourable, as they healed with no scar within a week, while the remaining three evolved to a sloughy wound, requiring further wound treatment. In the event of a suspected spider bite, further research is recommended into ways to identify the species, and into the use of nanocrystalline silver as an incipient treatment.
Author B. GreenSource: Wound Healing Southern Africa 5, pp 12 –17 (2012)More Less
For many years, management of chronic wounds, e.g. pressure ulcers, has been based on an understanding of the physiology of acute wounds. Both acute and chronic wounds need to follow all four would healing phases, namely haemostasis, inflammation, proliferation, and maturation or remodelling, in order to achieve wound closure. However, very often, the initiating mechanism of injury in chronic wounds does not require haemostasis.
Author A. ZoepkeSource: Wound Healing Southern Africa 5, pp 19 –22 (2012)More Less
Diabetes affects an estimated 16 million people in the USA. Just over half are aware that they have the disease. It is one of the leading causes of disease-related deaths in the USA. Diabetes and its related complications claim the lives of approximately 190 000 Americans annually. In South Africa, the situation is just as dire. Between four to six million people have diabetes.
Effect of topical propolis and dexamethasone on the healing of oral surgical wounds : original researchSource: Wound Healing Southern Africa 5, pp 25 –30 (2012)More Less
Background : The aim of the study was to determine the effects of the topical administration of propolis and dexamethasone on oral surgical wounds.
Method : Surgical wounds were made on the dorsum of the tongues of 90 hamsters, which were then divided into three experimental groups. The wounds were submitted to topical applications of a 30% ethanolic extract of propolis (EEP) (Group 1), 0.1% dexamethasone in orabase gel (Group 2), and orabase gel alone (Group 3). Six animals from each subgroup were sacrificed on days 1, 3, 7, 14, and 28 post surgery. Statistical analysis, involving nonparametric Kruskal-Wallis and Mann-Whitney tests and a chi-square test, were used to compare categorical variables.
Results : The macroscopic exam of the surgical sites revealed statistically significant differences in the wound area between the propolis group and the remaining groups on day 7 post-operatively (p-value = 0.002). In the microscopic exam, the effects of EEP and dexamethasone were compared with regard to the presence of necrotic tissue, intensity of inflammation, formation of granulation tissue and epithelialisation.
Conclusion : In conclusion, our results showed that EEP demonstrated a greater anti-inflammatory effect and shorter healing time in oral surgical wounds in hamsters, in comparison to dexamethasone in orabase gel.
Reduction of bacterial burden and pain in chronic wounds using a new polyhexamethylene biguanide antimicrobial foam dressing : clinical trial results : original researchSource: Wound Healing Southern Africa 5, pp 31 –36 (2012)More Less
Objective : A randomized controlled trial to evaluate the effectiveness of a polyhexamethylene biguanide (PHMB) foam dressing compared with a similar non-antimicrobial foam for the treatment of superficial bacterial burden, wound-associated pain, and reduction in wound size.
Setting and participants : This study was conducted in 2 wound healing clinics - a university hospital-based clinic and a community-based clinic. Forty-five chronic wound subjects, stratified to either foot or leg ulcers, were followed for 5 weeks.
Method : A multicenter, prospective, double-blind, pilot, randomized controlled clinical trial with 3 study visits (Weeks 0, 2, 4) documented pain and local wound characteristics using NERDS and STONEES clinical criteria to determine superficial bacterial damage or deep/surrounding infection.
Results : The use of PHMB foam dressing was a significant predictor of reduced wound superficial bacterial burden (P = .016) at week 4 as compared with the foam alone. Pain reduction was also statistically significant at week 2 (P = .0006) and at week 4 (P = .02) in favor of the PHMB foam dressings. Polymicrobial organisms were recovered at week 4 in 5.3% in the PHMB foam dressing group versus 33% in the control group (P = .04). Subjects randomized to the PHMB foam dressing had a 35% median reduction in wound size by week 4, compared with 28% in the control group.
Conclusion : PHMB foam dressing successfully reduced chronic wound pain and bacterial burden.
Source: Wound Healing Southern Africa 5, pp 52 –59 (2012)More Less
This index is an extension of the WHSA Wound Care Classification. The index is by no means comprehensive or preferential and includes a small selection of products that have been recently advertised or promoted in Wound Healing Southern Africa. Please refer to standard wound care textbooks or WHSA Wound Care Classification for a more comprehensive product overview. The products' full package inserts should be consulted for directions of use and contra-indications. This index is not intended to be prescriptive, nor does it replace good clinical judgement. All efforts have been made to ensure that the information is accurate. WHSA, the publisher and the companies represented here may not be held liable for any mistakes resulting from the use of this index.