oa Central African Journal of Medicine - Appetite and weight gain in children: A double-blind trial using cyproheptadine and methandrostenolone

Volume 15, Issue 10
  • ISSN : 0008-9176



Ninety-eight anorexic, underweight but otherwise normal children were investigated in a double-blind trial utilising cyproheptadine, a placebo and methandrostenolone. The appetite stimulating properties of cyproheptadine and the concomitant effect on weight gain were clearly demonstrated. A group of children taking both cyproheptadine and methandrostenolone together showed by far the greatest increase in weight. It is suggested that this effect of cyproheptadine could be utilised clinically.

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