oa Central African Journal of Medicine - The vogue In renal physiology a review article

Volume 16, Issue 8
  • ISSN : 0008-9176



Salt and water balance are controlled by three factors: (a) Vasopressin is mainly concerned with the conservation of water. (b) The renin-angiotensin-aldosterone system regulates sodium excretion. (c) The sympathetic vasomotor nerves can prevent the loss of both sodium and water. All three factors operate, in part at least, by changing the proportion of superficial cortical to deep juxta-medullary nephrons that are functioning at any one time. A shift of activity from the superficial to the deep nephrons can be a very effective means of avoiding an unnecessary loss of salt and water in the urine.

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