oa Central African Journal of Medicine - Iron overload

Volume 18, Issue 2
  • ISSN : 0008-9176



1. Iron overload is common in Rhodesian Africans. 2. It is more common and severe in men than women. 3. Its prevalence and degree in both sexes increases with age. 4. Its prevalence and degree are similar to those found in the South African Bantu. 5. The principal source of the iron is homebrewed African beer. 6. Iron absorption is enhanced by protein malnutrition. 7. It plays no part in the aetiology of carcinoma of liver and probably does not produce cirrhosis. 8. It promotes bacterial growth and is responsible for primary peritonitis and endotoxic shock in subjects with severe siderosis. 9. The iron overload seen in the black peoples of Southern Africa is distinct from idiopathic haemochromatosis. 10. When severe siderosis and scurvy occur together osteoporosis especially of the lumbar vertebrae results.

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