oa Central African Journal of Medicine - Hycanthone in 1,035 Cases of Vesical Schistosomiasis

Volume 18, Issue 6
  • ISSN : 0008-9176



A total of 1 035 patients with vesical schistosomiasis were treated with hycanthone. The over-all cure rate in 1 001 patients, followed up two months after the first treatment, was 90 per cent. and the cumulative cure rate, after the fourth treatment, was 99,5 per cent. 3 The compound was generally well tolerated; side effects were usually mild or moderate and hospitalization was not needed in any of the patients. 4 The results of the trial indicate that hycanthone mesylate is highly effective in the treatment of S. haematobium infection and in view of the fact that it is administered in a single dose, we consider it the best drug, available at present, for the mass treatment of the disease.

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