oa Central African Journal of Medicine - Therapeutic screening to differentiate malaria from other tropical syndromes

Volume 19, Issue 8
  • ISSN : 0008-9176



Combined therapy with a single dose of sulphamethoxazole (SMZ) and trimethoprim (TM), as BACTRIM (ROCHE), was found to be effective alone for the treatment of Plasmodium falciparum infection. The TM and SMZ t herapy was 100 per cent effective in control of the clinical disease, without any recrudescences. This combined therapy is suggested as the ideal antimalarial drug; as the trial shows this therapy is the least toxic and unlikely to result in the development of any resistant strains of P. Falciparum malaria.

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