oa Central African Journal of Medicine - The hookworm problem in the Rhodesian Lowveld:its importance and treatment

Volume 20, Issue 5
  • ISSN : 0008-9176



1. The hookworm problem in the lowveld region is a complex one, involving Necator americanus, Ancylostoma duodenale and Ternidens deminutus. 2. While loads recorded were generally low, this fact plus the high prevalance, create a threat, unless the position is watched carefully. With the expansion of irrigation systems, the widespread hookworm infection may develop into a widespread hookworm disease. 3. Although we were unable to demonstrate any significant difference in working capacity of labourers harbouring low and high loads of hookworm, it may be that such effects were masked by the multiple nature of most of the parasitic infections. 4. Given a single dose regimen of 10 mg/kg or 20 mg/kg, Pyrantel pamoate proved extremely safe and effective in the treatment of Ternidens deminutus and Ancylostoma duodenale infections. For infections with Necator american us, a three-day course of treatment is recommended.

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