oa Central African Journal of Medicine - A re-assessment of the epidemiology and clinico-pathological features of human trypanosomiasis in Rhodesia

Volume 21, Issue 12
  • ISSN : 0008-9176



Misconceptions have arisen over the years as to the status of human trypanosomiasis in Rhodesia. The true status and features of the disease are presented in two sections. ere conducted in the endemic rea to find ""healthy carriers"" with negative results. Mass screening of serum immunoglobulin M (IgM ) was not found to be of use in the detection of new cases. High IgM levels were found in the local populace in the absence of trypanosomiasIs. 2. Clinico-pathological features. Nearly all the recorded cases of trypanosomiasis between 1968 and 1974 are subject to an analysis based on clinical observations, laboratory and pathological findings. As a result of these findings it is shown that the disease affects the European and African differently although still potentially fatal in both races. It is suggested that the criteria for the diagnosis of late stage (cerebral) trypanosomiasis will have to be redefined.

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