oa Central African Journal of Medicine - A preliminary study on the treatment of filariasis due to dipetalonema perstans

Volume 25, Issue 3
  • ISSN : 0008-9176



Dipetalonema perstans is a filarial worm which is fairly widely distributed through Africa and South America. Most authors consider that the species is a commensal in man but others have long maintained that it may be pathogenic, causing allergic reactions which may be especially severe in the European patient. Until recently, no effective treatment has been available for D. perstans infections and diethycarbamazine has proved singularly ineffectual. The present paper reports on a long term study on the use of mebendazole alone at a .dose of 400 mg b.d. for 14 days and a combination of mebendazole 100 mg b.d. and levamisole 50 mg daily for 14 days on two European males.

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