oa Central African Journal of Medicine - Bioavailability and the practitioner

Volume 26, Issue 7
  • ISSN : 0008-9176



""Bioavailability"" is a term that has been heard with increasing frequency over the past few years. Despite the exposure it is however still not fully understood. To many the issue is limited to a comparison of the proprietary name versus the generic name. ""Generic equivalence"" however is a separate issue. Inequivalence of bioavailability for any product, be it the generic or proprietary form of one drug, different proprietary forms of the same drug or the same proprietary form manufactured on separate occasions, may have clinical significance. Another view of bioavailability is that it can be equated with drug quality. Quality is certainly important but it is only part of a much larger question of comparable performance in vivo.

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