oa Central African Journal of Medicine - Disc sensitivity of Gonococci to Rosoxacin, Tetracycline and S-Lactam antibiotics

Volume 29, Issue 11
  • ISSN : 0008-9176



Of 175 strains of N. gonorrhoeae included in this study 64 (37%) were shown to be penicillinase- producing. All of the strains were fully sensitive in vitro to rosoxacin and tetracycline. The incidence of PPNG has trebled in the last year, and the use of 8-lactam antibiotics as the first-line drug for the treatment of gonorrhea may thus have to be reconsidered. Alternative treatment regimes must take into account availability, cost, side-effects and patient compliance as well as sensitivity of the organism.

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