oa Central African Journal of Medicine - What causes neonatal jaundice in Harare?

Volume 29, Issue 5
  • ISSN : 0008-9176



A prospective and a retrospective study were carried out in Harare Hospital neonatal unit, the first to establish the causes of severe jaundice in babies and the second to determine the reasons for exchange transfusion and the morbidity of this procedure. ABO incompatability is much the commonest cause of jaundice, contributing 56% in the prospective and 60% in the exchange transfusion study. The next commonest causes in both groups were septicaemia (12%) glucose 6- phosphate dehydrogenose deficiency (10%) and Rh incompatibility (5%). The mortality rate from exchange transfusion in the retrospective study was 17.6%. Management of ABO incompatibility at primary level is discussed.

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