oa Central African Journal of Medicine - Penicillinase producing Gonococci

Volume 30, Issue 12
  • ISSN : 0008-9176



Gonorrhoea has been descriptionbed as one of the most prevalent communicable diseases of man, and is one -of the few infectious diseases that continue to increase in incidence throughout the world. Despite gradual increase in resistance the treatment of gonococcal infection with penicillin has for many years been successful because the sensitivity of the organism has remained within the levels that could be achieved with a single dose of this antibiotic. In 1976 however, strains of Neisseria gonorrhea isolated in Britain and the United States were found to have acquired the ability to produce B-lactamase, an enzyme that disrupts the B-lactam ring of penicillin and other related�antibiotics.

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