oa Central African Journal of Medicine - Compliance with anti-Tuberculous chemotherapy in Harare city

Volume 30, Issue 8
  • ISSN : 0008-9176



We studied retrospectively 290 patients diagnosed as having tuberculosis within the period 1.6.80 - 31.5.81 and fully managed by the MuniciPal TB service during the succeeding 18 months bftherapy, to determine 1) compli'ance with therapy and 2) factors which may affect compliance, - age, sex nature of employment, type ofTB, treatment as outpatient or inpatient, and, if so. duration of inpatient treatment. Fifty-eight percent of patients completed therapy without default, and a further 24% were traced and recalled to therapy without significant interruption of treatment. Eighteen percent failed to complete therapy and were lost to follow-up. In both the default and non-default groups, 24% of patients were age 16 or under, the male:female ratio was 3: 1, and 84 % of cases were pulmonary tuberculosis. Of the defaulters, 8% were treated as outpatients, and the mean in patient stay was 6,7 weeks (range 1-26 weeks). In the non-default group, 9% were outpatients and the inpatient stay was 7,1 weeks (range 1-26 weeks). Social class (as judged by employment) highlighted several ""at risk"" groups for default: the unemployed, labourers, housewives and children. The reason for default amongst these groups is largely speculative, but migration between urban and rural areas is probably the most important, and is potentially remediable.

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