oa Central African Journal of Medicine - Congenital malaria at University of Calabar Teaching Hospital with reference to haemoglobin and immunoglobulin

Volume 31, Issue 12
  • ISSN : 0008-9176



Congenital Malaria can occur in the absence of any evidence of active malaria in the mother and also in the absence of demonstrable damage to the placenta (infarcts). Plasmodium falciparum is the most widely spread malaria parasite in Calabar and in spite of massive placental infection there could be absence of infection in the neonate. While crescents were never found in the placental blood, signet rings were seen in the placental tissue showing that neonates are most likely to be infected with signet rings. Significant differences were not observed between the birth weight and parasitaemia. It is clear from our work that causes other than malaria were the cause of decreased haemoglobin in pregnant women. The decrease in IgG from gravidae 1 to 5 (corresponding ages 18,4 to 25,2 years) and the increase from gravidae 5 to 9 (corresponding ages 25,2 to 32,5 years) showed that the number of pregnancies and age affected the immunoglobulin levels. It appears that immunoglobulin levels seem to be depressed in pregnancy even in the presence of parasitaemia.

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