oa Central African Journal of Medicine - Hepatocellular carcinoma presenting as a fever of undetermined origin

Volume 31, Issue 2
  • ISSN : 0008-9176



Fever and malignancy frequently co-exist and a fever is present in a third of patients with hepatocellular carcinoma (HCC) The diagnosis of HCC is often clinically obvious when the patient is first seen and a mild fever is almost incidental and often ignored. Indeed two papers discussing the systemic manifestations of HCC do not mention fever as a feature. This article descriptionbes two patients who presented with a marked sustained pyrexia and none of the clinical features classically associated with this malignancy but had histologically proven HCC.

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