oa Central African Journal of Medicine - Correlation studies between concentrations of glycosylated haemoglobins and lipids in noninsulin- dependent Nigerian diabetics

Volume 32, Issue 10
  • ISSN : 0008-9176



A study was made to establish the relationship between plasma concentrations of glycosylated haemoglobin and lipids in 75 non-insulin-dependent Nigerian diabetics. A significant negative correlation was observed between the concentrations of glycosylated haemoglobin and high density lipoprotein (HDL) levels in female diabetics (r = - 0,359, p < 0,05) and in the patients as a whole (r = - 0,29, p < 0,05) but these values did not correlate in the male diabetics. No correlation was observed between HDL cholesterol and glycosylated haemoglobins in either male or female non-diabetic Nigerians. There was lack of correlation between glycosylated haemoglobin levels and plasma levels of total cholesterol and triglycerides in the diabetics. There was also no significant correlation between plasma triglycerides and HDL-cholesterol levels. The total mean concentrations of glycosylated haemoglobins, HDL-cholesterol, total cholesterol and triglycerides were not affected by sex. Our results suggest that the estimation of plasma DL cholesterol may be of more clinical significance in female than male Nigerian diabetics and a useful parameter in identifying diabetics with a high risk of developing long-term complications.

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