oa Central African Journal of Medicine - Microbial pathogens associated with diarrhoea in children admitted to Harare hospital for rehydration therapy

Volume 32, Issue 5
  • ISSN : 0008-9176



Stool specimens from 236 children admitted to Harare Hospital with acute diarrhoea were examined for bacterial, viral and parasitic pathogens. Results were compared with specimens from 192 control patients admitted to the same hospital for other reasons. C. jejuni (13,6% diarrhoea, 2,1% controls) and EPEC (10,3% diarrhoea, 2,6% controls) were the most common pathogens isolated, and were isolated only from children under two years. Other bacterial pathogens were isolated from older children as well as infants, while parasites were isolated mainly from children over two years of age. Virus particles were detected by EM in only two patients, both with diarrhoea. Of the EPEC strains isolated from children with diarrhoea, the majority belonged to five serotypes and these serotypes were uncommon in controls. The significance of C. jejuni as a major cause of summer diarrhoea in infants in Zimbabwe is demonstrated, but further studies are recommended to investigate microbial pathogens.

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