oa Central African Journal of Medicine - Phage-types and resistance pattern of staphylococcus aureus, isolated from clinical specimens, to penicillin and cloxacillin in a Lagos hospital

Volume 32, Issue 7
  • ISSN : 0008-9176



Three hundred and twelve clinical specimens of wounds, pus, aspirates, blood and high vaginal swabs (HVS) collected from patients in Lagos University Teaching Hospital were investigated for the presence of staphylococci. Of these, 81 (26%) yielded Staphylococcus aureus. The Staph. aureus positive specimens included 50 wound swabs out of 128 (39%); 9 HVS out of 34 (27%); 18 pus out of 79 (23%); 2 blood out of 23 (9~); and 2 aspirates out of 28 (7%). Of the 81 isolates 75 were phage typable. The commonest group was phage group 111 to which 42 (51,9%) of the strains belonged. The untypable strains were generally more resistant to antibiotics. About 99% and 28% of the 81 strains were resistant to penicillin and cloxacillin respectively. Continuous monitoring of Staph. aureus isolates by phage typing and antibiotic sensitivity in a hospital setting is emphasized.

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