oa Central African Journal of Medicine - Hyperprolactinaemia in Zimbabwean women

Volume 33, Issue 7
  • ISSN : 0008-9176



Serum prolactin concentrations were measured in 280 women with symptoms of menorrhoea, galactorrhoea, or both, seen in the gynaecology endocrine clinic of Parirenyatwa Hospital between 1981 and 1985. Two hundred and twenty women had normal prolactin levels and 60 were found to have hyperprolactinaemia. Of the 20 women who complained of galactorrhoea alone hyperprolactinaemia was detected in 10 of them, of whom 2 had abnormal sella turcica. Twenty-four women with secondary amenorrhoea had sustained hyperprolactinaemia and 2 of them had abnormal skull X-rays. Of the 17 women with amenorrhoea and galactorrhoea 9 had hyperprolactinaemia and 3 out of 9 (33%) had radiologically demonstrable pituitary tumours. The overall incidence of hyperprolactinaemia in amenorrhoenic women (33 from 260 patients) was 12 per cent. Of the 33 women with hyperprolactinaemic amenorrhoea 5 had pituitary tumours (15%). It is concluded that pituitary tumours are not a major cause of hyperprolactinaemia in African women.

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