oa Central African Journal of Medicine - Non-Hodgkin's lymphoma of high and intermediate grade in black Zimbabweans

Volume 33, Issue 8
  • ISSN : 0008-9176



A study of patients with intermediate and high grade non-Hodgkin's lymphoma presenting to the medical units in Harare over a three-year period was carried out. Seventy-four patients were seen and high grade malignancy was more common than intermediate. Ages ranged from 8 to 73 years and a male predominance was seen in all sub-groups. Although the stated duration of symptoms was not excessive, in most cases disease was extensive at presentation. Excluding Burkitt's lymphoma, which was considered separately, the primary disease site was extra-nodal in 29,9 per cent with the gastro-intestinal tract being the most common extra-nodal site. Systemic symptoms were experienced by more than half the patients. In most high and intermediate grade lymphoma groups the general clinical features resembled those reported in developed countries, with the most striking differences being the advanced stage, and high bulk of disease observed in this series. In Burkitt's lymphoma the features were not typical of the African pattern and more closely resembled that seen in America.

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