1887

oa Central African Journal of Medicine - Plasma lipids and lipoprotein-cholestrol distribution in nephrotic syndrome patients during short term high dose steroid treatment

Volume 39, Issue 10
  • ISSN : 0008-9176

 

Abstract

Plasma lipids and lipoprotein-cholesterol profiles were studied in 11 consecutive patients (eight females and three males) with the nephrotic syndrome (NS) during a short term treatment with high dose prednisolone. A significant fall from the high mean pre-treatment levels of total cholesterol and LDL-cholesterol was demonstrated at four, eight and 12 weeks of treatment (p < 0,005) while the fall in the mean triglyceride level only became significant at eight weeks (p < 0,01). The mean HDL-cholesterol level did not change significantly throughout, although there was a significant rise in the mean HDL-cholesterol total cholesterol ratio at four weeks (p = 0,01) and at both eight and 12 weeks (p < 0,005). The study has demonstrated a significant improvement in the lipids and lipoprotein-cholesterol profile of patients with the nephrotic syndrome during a shortterm high dose steroid treatment.

Loading full text...

Full text loading...

Loading

Article metrics loading...

/content/CAJM/39/10/AJA00089176_26
1993-10-01
2019-08-21

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error