oa Central African Journal of Medicine - Skin irritant and tumour promoting extract from the latex of Euphorbia bougheii

Volume 39, Issue 3
  • ISSN : 0008-9176



A crude ethylacetate extract was isolated from Euphorbia bougheii by a combination of solvent-solvent and chromatographic methods. The extract exhibited significant skin irritant activity on the mouse ear as well as a tumour promoting activity on the mouse back skin. This indicates that the use of this plant as a medicine must be discouraged since the latex extract causes cancer.

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