oa Central African Journal of Medicine - Chemotherapy as an adjunct to spraying in malaria control in Southern Rhoderia

Volume 8, Issue 5
  • ISSN : 0008-9176



Two similar areas, Fungwe and Chimanda, in Southern Rhodesia, were each sprayed with BHC annually for seven years. After five years parasite rates remained in the region of 20 percent and mass chemotherapy was undertaken in one of the areas. As many people as possible were treated on each of three occasions in the Fungwe area, using a dose of 600 mg. chloroquin base and 50 mg. pyrimethamine. Treatment was at the beginning of the transmission season in 1959 in the middle of the next non-transmission season and at the end of the second transmission season. Parasite rates in the area fell rapidly after these experimental treatments from 23.5 percent to 2.58 percent during the period of the experiment (18 months). In the control area the parasite rate remained at approximately 20 percent. Detailed figures are given of the parasite rates at the different seasons in both areas. It is considered that malaria control projects in rural Africa do not sufficiently take into account people who, for one reason- or another avoid treatment or having slides taken and who form foci of infection of unknown importance.

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