oa African Zoology - Glucose tolerance in Bufo gutturalis (power) after destruction of the islets of Langerhans

Volume 17, Issue 1
  • ISSN : 1562-7020
  • E-ISSN: 2224-073X



An investigation was undertaken to determine the glucose tolerance response in Sufo gutturalis after alloxan induced diabetes. The pancreatic ?-cells were completely destroyed 24 h after the administration of 240 mg alloxan/kg body mass. However, animals treated in this manner showed a normal response curve. When the alloxan dosage and treatment period were increased, typically diabetic tolerance was apparent.

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