oa African Zoology - Histidine and carnosine reduce muscle fatigue in Xenopus laevis

Volume 19, Issue 3
  • ISSN : 1562-7020
  • E-ISSN: 2224-073X



The inclusion of either histidine or carnosine in a frog Ringer's perfusate at a concentration of 20 mmol/dm� reduced fatigve in the gastrocnemius muscle of Xenopus laevis significantly. Histidine was superior to carnosine in this respect. The evidence also suggests that muscles perfused with histidine exhibit superior recovery, accumulate less lactic acid and lose significantly less K + from the intracellular fluid. The implications of these findings in future research on capture myopathy are discussed.

Loading full text...

Full text loading...


Article metrics loading...


This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error