oa African Zoology - Thyrocalcitonin studies in elasmobranch fish

Volume 4, Issue 1
  • ISSN : 1562-7020
  • E-ISSN: 2224-073X



We recently reported a hypocalcaemic and hypophosphataemic action of mammalian thyrocaltitonin in the teleost fish Ictalurus melas (Louw, Sutton and Kenny 1967). A logical sequence to these studies would be to examine the action of the same hormone in elasmobranch fish. The absence of an osseous skeleton in the latter provides ideal material to test the hypothesis that the mode of action of thyrocalcitonin is due to a direct effect upon bone. Moreover, in contrast to the diffusely distributed thyroid follicles of the teleost fish, the thyroid of the elasmobranch fish is a discrete gland which greatly facilitates extraction procedures. We have therefore examined the effects of porcine thyrocalcitonin on the levels of serum calcium and phosphate in the lazy shark Poroderma africanum (Gmelin) (Smith 1949). In addition the thyroid glands from the school shark Galeorhinus galeus (Linnaeus) (Smith 1949), were assayed for hypocalcaemic activity.

Loading full text...

Full text loading...


Article metrics loading...


This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error