n African Journal for Physical Health Education, Recreation and Dance - A profile of Isoniazid Tuberculosis Preventive Therapy treatment defaulters in Botswana : utilization of primary health care services

Supplement 2
  • ISSN : 1117-4315


Tuberculosis is the main cause of morbidity and mortality among People Living with HIV/AIDS (PLHIV) globally, and this co-infection has negative treatment outcomes. Because of its high HIV prevalence, Botswana also experiences a high rate of HIV/TB co-infection. In 2001 Botswana implemented a nationwide Isoniazid Preventive Therapy (IPT), which is provided for all patients diagnosed with HIV. However, several studies have reported on high defaulter rates for patients enrolled in the IPT programme. This study profiles the characteristics of IPT defaulters in Botswana. A quantitative, retrospective and descriptive design was used to collect data from records of patients enrolled in the IPT programme between 2008 and 2009. Data were collected from IPT and TB records from 24 health facilities across 8 districts in Botswana, using structured data abstraction tools. Of the 1007 patient records reviewed, 655 (65%) were defaulters. Males defaulted more than females, and the defaulter rate was highest amongst those aged below 20 years (74%) and those between 21 and 30 years (70.3%). Most clients defaulted within the first two months of initiation of IPT. Defaulting rates across the 24 health facilities ranged from 39% to 86% with an average rate of 62.6%. In order to improve the treatment completion rate, the IPT programme should seek ways of targeting specific groups as well as districts and health facilities with the highest defaulting rates.

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