n Suid-Afrikaanse Tydskrif vir Natuurwetenskap en Tegnologie - Kombinasies van inhibeerders van glukosedraers en estroonanaloë op borskankersellyne : referaatopsomming

Volume 33, Issue 1
  • ISSN : 0254-3486
  • E-ISSN: 2222-4173



Combinations of chemotherapeutic agents are commonly used in the clinical setting as this allows for a reduction in the dose of each agent, and thus reduced toxicity, with increased therapeutic efficacy. This study proved the feasibility of synergy between two novel oestrone analogues and GLUT inhibitors. The synergistic combinations which have been identified indicate that the different molecular subtypes of breast cancer, as represented by the cell lines used, respond differently to the combination therapy. These differences will be further investigated.

Loading full text...

Full text loading...


Article metrics loading...


This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error