oa Current Allergy & Clinical Immunology - Work-related anaphylaxis : review article

Volume 21 Number 4
  • ISSN : 1609-3607



A definition of anaphylaxis was recently agreed to at an international symposium on this subject. This article proposes a definition for work-related anaphylaxis that is conceptually consistent with similar classifications for work-related asthma and rhinitis, which defines two major categories - occupational anaphylaxis and work-exacerbated anaphylaxis. The epidemiology and causative agents implicated in work-related anaphylaxis are outlined, with a focus on the most commonly implicated agents such as natural rubber latex, insect venoms, food proteins, disinfectants and pharmaceutical drugs. Diagnosis, management and prevention are discussed. Prevention of work-related anaphylaxis revolves around making a concerted effort to identify the trigger so that more effective primary, secondary and tertiary interventions can be implemented.

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