oa Current Allergy & Clinical Immunology - Food protein-induced enterocolitis syndrome (FPIES) - a review : review article

Volume 22, Issue 2
  • ISSN : 1609-3607



Food protein-induced enterocolitis syndrome (FPIES) is an under-recognised and frequently misdiagnosed syndrome - characterised by severe protracted diarrhoea and / or vomiting and frequently associated with additional symptoms such as pallor and / or lethargy - which has its onset soon after the ingestion of the particular food protein. FPIES represents a severe cell-mediated, gastrointestinal food hypersensitivity. Although typically ascribed to to cow's milk and soy, FPIES has been described after the ingestion of a wide range of food proteins.

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