oa Current Allergy & Clinical Immunology - Beware the rare cause of an acute abdomen - : case report

Volume 23, Issue 1
  • ISSN : 1609-3607



Acute abdomen in school-age children can have a surgical or non-surgical aetiology. The commonest cause is acute appendicitis, a medical emergency requiring an urgent laparotomy. Less common causes of acute abdomen include acute bacterial enterocolitis (e.g. Yersinia, Campylobacter), trauma, Meckel's diverticulitis, basal pneumonia, inflammatory bowel disease, acute pancreatitis and urinary tract infections. Hereditary angio-oedema (HAE) is a rare but well-recognised cause of severe acute abdominal pain in children. HAE is an inherited disorder (autosomal dominant) of C1 inhibitor (C1 INH) with an estimated prevalence of 1 in 50 000. However, 25% of cases are sporadic.

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