oa Current Allergy & Clinical Immunology - A case report of transplant-acquired allergy in a child post liver transplant - : case report

Volume 27, Issue 3
  • ISSN : 1609-3607



Transplant-acquired allergy (TAA), previously described as transplant-acquired food allergy (TAFA), is an infrequent but potentially serious complication of organ transplantation. It has been described mainly after liver transplantation, but also after bone marrow, intestinal, lung and heart transplantations. The onset of the allergic symptoms starts many months after the transplant and ranges from symptomatic eosinophilic gastrointestinal inflammation to life threatening anaphylaxis. The pathogenesis is still not understood but appears to be a complex interplay between multiple factors including donor and recipient factors, the type of organ transplanted as well as the type of post-transplant immunosuppressive therapy protocol. We report on an 8 year old girl who developed de novo severe multiple food allergies, debilitating eczema and anaphylaxis 18 months after undergoing a liver transplant. She responded well to supportive management and a targeted elimination diet.

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