oa Current Allergy & Clinical Immunology - Atopic eczema : ABC of allergy

Volume 27, Issue 3
  • ISSN : 1609-3607



Dr Do-A-lot explains that eczema is a relapsing, inflammatory condition of the skin that results in a defective skin barrier.

This results in a loss of moisture from the skin and allows for easy access by microbes, especially Staphylococcus Aureus.
Importantly, affected skin is always itchy.
In atopic eczema genetic factors play a role, and the inflammatory process is mediated by immunoglobulin-E (IgE) in response to exposure to environmental allergens which might include foods or inhaled allergens like house dust mite (HDM), pollens or animal dander.
It typically affects infants and young children with a family history of atopy or a personal history of allergic disease like food allergy or asthma.

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