oa Current Allergy & Clinical Immunology - Focus on the home environment : three patients with hypersensitivity pneumonitis in one family - : case report

Volume 27, Issue 3
  • ISSN : 1609-3607



Repeated inhalation of organic antigens is a main cause of hypersensitivity pneumonitis (HP). We reported three patients with mould-induced HP from one family residing in a wet environment. Measures to minimise antigen exposure resulted in regression of HP. This highlights the association between HP and domestic environment, and emphasises the importance of environmental control in HP treatment.

Hypersensitivity pneumonitis (HP), also known as extrinsic allergic alveolitis (EAA), is a diffuse inflammatory lung disease caused by repeated inhalation of various antigens derived from fungi, bacteria, and animal and plant proteins or reactive inorganic compounds in sensitised individuals. Fungi represent a large source of antigens capable of causing HP, which is often related to the patient's occupation or domestic environment. Three patients diagnosed with HP from one family, residing in a wet environment, were reported here.

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