oa Current Allergy & Clinical Immunology - Adverse drug events : why we care : review article

Volume 28, Issue 4
  • ISSN : 1609-3607



Adverse drug reactions (ADRs) play an important role in the rational and safe use of medicines. ADRs occur in 10% of patients prescribed a medicine in the primary health care setting. Approximately 5% of all hospital admissions are due to an ADR and 10% of patients in hospital will develop an ADR. ADRs are a major burden on often stretched healthcare systems, with substantial economic impact. Many ADRs are preventable and an awareness of these risks are paramount in terms of the prevention of patient harm.

This article will provide a broad overview of the epidemiology of ADRs, their costs to the healthcare system, a simple classification for ease of recognition, causality assessments and the importance of pharmacovigilance as well as ADR reporting.

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