n Cardiovascular Journal of Africa - Mini-sternotomy approach for aortic valve replacement in a patient with osteogenesis imperfecta : online article - case report

Volume 24, Issue 9
  • ISSN : 1995-1892
  • E-ISSN: 1680-0745



Osteogenesis imperfecta (OI) is a heritable disorder of the connective tissue. Cardiovascular involvement is rare, related mainly to aortic valve regurgitation. Open-heart surgery in these patients is associated with increased morbidity and mortality rates as a result of tissue friability and bone brittleness as well as platelet dysfunction. We present a patient with OI who underwent successful aortic valve replacement with a mini-sternotomy approach.

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