1887

oa South African Journal of Chemistry - The alkaloids of the Leguminosae : part II2. Hofmann degradative studies on calpurnine from Calpurnia subdecandra

Volume 19, Issue 2
  • ISSN : 0379-4350

 

Abstract

The axial configuration of the 13-hydroxyl group in 13-hydroxysparteine and hence 13-hydroxylupanine is confirmed by comparative rate studies on the hydrolysis of the acetate and of the epimeric acetate. Hofmann degradation of 13-hydroxylupanine methiodide gave a methine (II; R1 + R2=O, R3 = OH, R1 = H, R5 = CH3) and starting material. 13-Hydroxylupanine dihydromethine and 13-oxolupanine dihydromethine could not be degraded by the Hofmann reaction. The Hofmann degradation cannot therefore be used for the stepwise degradation of the D-ring in 13-hydroxylupanine.

Loading full text...

Full text loading...

Loading

Article metrics loading...

/content/chem/19/2/AJA03794350_1156
1966-10-01
2016-12-10

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error