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oa South African Journal of Chemistry - Synthesis of novel piperazine-linked anthranilic acids as potential small molecule kinase inhibitors : research article

Volume 67, Issue 1
  • ISSN : 0379-4350

 

Abstract

Substituted anthranilic acid and piperazines were used as building blocks to prepare two libraries of compounds, with the aim being that they would exhibit biochemical activity as small molecule kinase inhibitors. The synthesized anthranilamidepiperazine compounds were subsequently tested against a panel of kinases including EGFR, Abl, Akt and Aurora B.

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/content/chem/67/1/EJC152901
2014-01-01
2016-12-11

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