n SA Pharmaceutical Journal - Biological therapy in rheumatoid arthritis – notes for the pharmacist - review

Volume 86 Number 5
  • ISSN : 2221-5875
  • E-ISSN: 2220-1017


Progress in understanding the molecular biology of rheumatoid arthritis has led to the development of targeted therapies designed to ameliorate this disabling disease and improve patient outcomes. Biologic-based therapies are being developed to target specific cytokines in the inflammatory pathway, such as tumour necrosis factor (TNF), T-lymphocytes, B-lymphocytes and interleukin-6 (IL-6). An overview of biological therapies for rheumatoid arthritis forms the basis of this article.

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