n Cardiovascular Journal of Africa - Fluorine-18 fluorodeoxyglucose positron emission tomography in assessing myocardial viability in a tertiary academic centre in Johannesburg, South Africa : a pilot study - cardiovascular topics

Volume 30 Number 6
  • ISSN : 1995-1892
  • E-ISSN: 1680-0745



Background: Positron emission tomography detects patients with myocardial contractile dysfunction secondary to ischaemic heart disease who may benefit from coronary revascularisation.

Methods: We reviewed technetium-99m sestamibi single-photon emission computed tomography (SPECT) and fluorine-18 fluorodeoxyglucose (F18-FDG) positron emission tomography (PET) data from 236 patients imaged between January 2009 and June 2015. The patients were grouped into three groups: no evidence of viability, viability 1–10% and viability > 10%.

Results: Viability exceeding 10% was evident in 55% of the patients. On multivariate analysis, aspirin intake [OR: 1.92; 95% CI: 1.08–3.41; p = 0.026] and hypertension [OR: 1.89; 95% CI: 1.07–3.33; p = 0.029] were clinical factors associated with the presence of myocardial viability.

Conclusion: Our study demonstrated that F18-FDG PET was able to identify 55% of patients with ischaemic heart disease with viability in more than 10% of the total myocardium when using a 17-segment model.

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