1887

oa SA Heart - Scorpion cardiotoxicity : cardiotoxic effects of Parabuthus, the South African scorpion - commentary

Volume 16 Number 4
  • ISSN : 1996-6741
  • E-ISSN: 2071-4602

 

Abstract

A range of cardiotoxic abnormalities occur in about one third to one half of patients with systemic envenomation. These effects include atrial tachycardia, ventricular extrasystoles, T wave inversions, ST-T wave changes and, less frequently, bundle branch block. Increased autonomic stimulation caused by increased vagal effects on the heart and sympathetic stimulation are the probable cause of these effects. Hypertension is common and occurs early in response to sympathetic stimulation. Hypotension is less common, occurs with the development of severe envenomation, and often requires intervention with vasopressors and fluid resuscitation. Many factors are at play in the development of hypotension, with cholinergic stimulation causing vasodilatation, fluid loss and myocardial depression.

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2019-11-01
2020-10-25

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