Journal of Minimum Intervention in Dentistry - latest Issue

Search result: One clinical trial was found.

Clinical outcomes: There appears to be no difference in the success rate of both types.

State of evidence and recommendations: The current level of clinical evidence to this topic is still limited in quantity and quality and more trials are needed in order to confirm these results.

[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not replace the need for a full systematic review report to the topic]

Search result: Three clinical trials with a laboratory component were found.

Clinical outcomes: There appears to be no difference in the pulp response between conventional GIC and CaOH-cement (CaOH is considered to be the gold standard in pulp treatment due to its high tissue supporting properties. Lack of difference between C-GIC and CaOH suggest high biocompatibility of C-GIC concerning pulp tissue).
 
State of evidence and recommendations: The current level of clinical evidence to this topic is still limited in quantity and more trials are needed in order to confirm these results. The quality of the existing evidence requires further assessment.

[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not replace the need for a full systematic review report to the topic]

Search result: Ten clinical trials were found and traced concerning high-viscosity conventional GIC. No trials were identified comparing strontium or calcium low-viscosity conventional GIC. All identified trials compared Fuji IX for strontium and Ketac Molar for calcium based GIC.

Clinical outcomes: The overall results suggest no difference between Fuji IX and Ketac Molar in the clinical outcomes of: recurrent caries, occlusal wear and colour match. Two of the 10 trials suggest a higher failure rate for Ketac Molar after 1 and 2 years. However, eight trials indicated no difference in failure rate after 1, 2, 3 and 6.3 years.

State of evidence and recommendations: All evidence from clinical, controlled trials. This is a new topic and the quality of the existing evidence requires further assessment.

[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not replace the need for a full systematic review report to the topic]

Search result: No clinical trials or 2-arm (controlled) trials of any design (in-situ, in-vitro) could be found. Only one single-arm/longitudinal in-situ trial was identified. This trial used the test subjects as control group (without CPP-ACP).

Clinical outcomes: The results of this trial showed an increase of the saliva pH in 16 out of 25 subjects after 3 weeks. A change from the initial level of pH 6.6 to the final level of around pH 7.6 was observed.

State of evidence and recommendations: The current level of evidence to this topic is still weak. Do to the lack of clinical trials no information are currently available about any clinical effect of CPP-ACP on the salivary pH of patients. The current results of the identified in-situ trial are only exploratory and require further investigation.

[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not replace the need for a full systematic review report to the topic]

Search result: One article, reporting on 2 clinical trials, was identified, concerning plaque pH-decrease after sucrose challenge: (a) comparison of CPP-ACP containing paste with no paste; (b) comparison of CPP-ACP containing paste with placebo.

Clinical outcomes: The results show a significant reduction in plaque pH fall after sucrose challenge with CPP-ACP containing paste.

State of evidence and recommendations: The results of both reported trials need to be regarded with caution due to: unclear reporting of study methods and results in text and tables; spelling errors in text; use of a ‘run-in phase’ before the trial. A run-in phase is a stage before a trial where patients are pre-selected that respond well to treatment. Such stage effectively excludes patients, introduces potential selection bias and thus generates risk of overestimation of subsequent trial results.

[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not replace the need for a full systematic review report to the topic]

Search result: Four clinical controlled trials were found.

Clinical outcomes: The results show that composite resin performs less satisfactory when compared to amalgam.

State of evidence and recommendations: The quality of the existing evidence requires further assessment.

[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not replace the need for a full systematic review report to the topic]