oa CME : Your SA Journal of CPD - Long-term consequences of antiretroviral therapy - : main article

Volume 23, Issue 5
  • ISSN : 0256-2170



Common sense in the management of lipodystrophy seems prudent. Behaviour modification, especially smoking and weight reduction, should be encouraged. Metabolic complications should be treated according to conventional guidelines for HIV-negative populations, but with regard for drug interactions with ART. Avoid PIs with atherogenic profiles in patients with other cardiovascular risk factors. <br>Identify lactic acidosis and peripheral neuropathy early. The best tool is a switched-on patient, who can let the astute clinician know well before the development of critical illness. <br>AIDS is a disease with 100% mortality if untreated. ART makes the vast majority of HIV-infected people better. Cardiovascular disease is treatable in most cases, and risk factors easily identified and addressed. Lipodystrophy, lactic acidosis, and peripheral neuropathy are usually identifiable by the informed patient and clinician. Use ART correctly, and deal with the consequences using clinical common sense.

Loading full text...

Full text loading...


Article metrics loading...


This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error