oa Journal of Endocrinology, Metabolism and Diabetes in South Africa - Lipohypertrophy - a complication of insulin injections

Volume 11, Issue 2
  • ISSN : 1608-9677
  • E-ISSN: 2220-1009



Extracted from text ... 64 JEMDSA November 2006, Vol. 11, No. 2 Lipohypertrophy and lipoatrophy of injection sites was a major problem with the old impure insulins.1 The problem improved somewhat with the advent of the monocomponent bovine and porcine insulins and the current pure human insulins, such that lipoatrophy in particular is now very rare.1, 2 However it now manifests more subtly, with thickening of the skin rather than the formation of lumps and pitting. Even diabetologists have been known to miss it, when not looking for it carefully. The complication has occurred with the new genetically engineered modified human insulins, with and ..

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