n Southern African Journal of HIV Medicine - Native valve endocarditis due to in an adult patient - : case report

Volume 14, Issue 3
  • ISSN : 1608-9693
  • E-ISSN: 2078-6751



endocarditis is rare, but associated with a high mortality. The most common species implicated is . The epidemiology of invasive infections is changing, with a predominance of non-albicans species causing invasive disease. We describe a case of endocarditis in an HIV-positive patient with pre-existing mitral valve disease and renal failure on haemodialysis. The patient presented with fever and malaise. Clinical examination revealed pulmonary oedema and severe mitral regurgitation. Blood cultures were positive for . β-D-glucan assay levels were elevated. An echocardiogram showed large, friable vegetations on the mitral valve. was cultured from the haemodialysis tip and the vegetations. The patient responded well to mitral valve replacement and antifungal therapy. A high index of suspicion and aggressive diagnostic modalities and therapy are essential in patients with candidaemia, to decrease mortality due to this condition.

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