1887

n South African Medical Journal - Rapidly progressive post-transplant lymphoproliferative disease following withdrawal of sirolimus : research

Volume 102, Issue 12
  • ISSN : 0256-9574
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Abstract

Sirolimus, a potent inhibitor of B- and T-cell activation, is a commonly used immunosuppressant after renal transplantation. Withdrawal of sirolimus from the immunosuppression regimen may reduce B-cell surveillance. We present a case of rapidly progressive central nervous system (CNS) polymorphic Epstein-Barr virus (EBV)-related post-transplant lymphoproliferative disorder following the withdrawal of sirolimus.

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/content/m_samj/102/12/EJC128986
2012-12-01
2016-12-10

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