oa South African Medical Journal - The inhibition of c-AMP-phophodiesterase by phenobarbitone

Volume 49, Issue 9
  • ISSN : 0256-9574
  • E-ISSN: 2078-5135



The early effects of phenobarbitone, theophylline, thyroxine and of combinations of these drugs, on rat liver microsomal aniline hydroxylase activity, were studied, and the results were compared with the effect of phenobarbitone on purified c-AMP-phosphodiesterase in vitro.

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