oa South African Medical Journal - Evaluation of a fixed combination of timolol maleate hydrochlorothiazide and amiloride hydrochloride in the treatment of hypertension - a long-term multicentre trial

Volume 58, Issue 6
  • ISSN : 0256-9574
  • E-ISSN: 2078-5135



The effect of a single daily dose of timolol, hydrochlorothiazide and amiloride hydrochloride in fixed combination (Moducren; MSD) in patients with mild to moderate essential hypertension was tested during 1978 in an open study covering 10 weeks per patient.

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